Bartonella Infections in Sweden: Clinical Investigations and Molecular Epidemiology
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Sequence variation in the ftsZ gene of Bartonella henselae isolates and clinical samples.
In a search for methods for subtyping of Bartonella henselae in clinical samples, we amplified and sequenced a 701-bp region in the 3' end of the ftsZ gene in 15 B. henselae isolates derived from cats and humans in the United States and Europe. The ftsZ sequence variants that were discovered were designated variants Bh ftsZ 1, 2, and 3 and were compared with 16S rRNA genotypes I and II of the s...
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To differentiate infectious endocarditis (IE) from other Bartonella infections and to identify infecting Bartonella bacteria at the species level on a serological basis, we used Western immunoblotting to test sera from 51 patients with Bartonella IE (of which 27 had previously benefited from species identification by molecular techniques), 11 patients with chronic Bartonella quintana bacteremia...
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Myocarditis and pericarditis are uncommon complications of human rickettsial, ehrlichial and Bartonella infections. Myocardial inflammation usually occurs in the setting of acute disseminated infection. Organisms associated with myocarditis include: Rickettsia rickettsii, R. conorii, Orientia tsutsugamushi, Coxiella burnetii, Anaplasma phagocytophila (the causative agent of Human Granulocytic E...
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6. Clarridge JE III, Raich TJ, Pirwani D, Simon B, Tsai L, Rodriguez-Barradas MC, et al. Strategy to detect and identify Bartonella species in routine clinical laboratory yields Bartonella henselae from human immunodefi ciency virus–positive patient and unique Bartonella strain from his cat. J Clin Microbiol. 1995;33:2107–13. 7. Mediannikov O, Cabre O, Qu F, Socolovschi C, Davoust B, Marié JL, ...
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The importance of Bartonella spp. as pathogens in animals is still unclear. Most infections appear to be asymptomatic. Some experimental infections, case reports and studies have suggested possible links to disease, but other studies have been unable to substantiate a role for Bartonella. Investigations are complicated by the high prevalence of infections in healthy animals, the uncertainties i...
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